Launaea pinnatifida Cass. A Species of the Controversial Drug Gojihva: Comprehensive Review

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D J Pandya
H T Makwana

Abstract

According to the Ayurvedic literature Launaea pinnatifida Cass is belong to the class of controversial drug Gohjiva. This plant is well known and valuable herb as per the traditional and Ethnobotanical information. This plant has been used since ancient time as herbal remedy for jaundice, diuretic, blood purifier and hepatoprotective action by the tribal people of the Western Ghats. However, the plant remains largely unexplored. Systematic pharmacognostical and phytochemical evaluation of the plant by means of standardization leads to the generation of data which is useful for future reference. The traditional medicinal activities suggest that it may yield important bioactive phytoconstituents. Present work dealing with the compilation of available data of Launaea pinnatifida (L. Pinnatifida) including pharmacognostical work, phytochemical studies and pharmacological work. Microscopic evaluation confirmed the presence of the lignified cork cells parenchyma with prismatic crystals. The histochemical study of root powder confirms the existence of mucilage, tannins, starch, lignin and crystals. Pharmacognostical studies revels the presence of many primary and secondary metabolites including carbohydrates, alkaloids, amino acids, glycosides, steroids and tannin in root powder. As far as phytochemical study is concern; only few phytochemical constituents have been isolated from L. pinnatifida including Taraxasterol from leaves taraxeryl acetate from the roots. Apart from this; triterpenoid saponins along with known compounds glutenol and hopenol B were isolated from Methanolic extract of seed of L. pinnatifida. Ethanol fraction of the leaves of L. pinnatifida has reported potent hepatoprotective activity, antimicrobial, antifungal and antioxidant activity.

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How to Cite
1.
Pandya D, Makwana H. Launaea pinnatifida Cass. A Species of the Controversial Drug Gojihva: Comprehensive Review. IJPPR [Internet]. 25Dec.2019 [cited 5Jul.2020];11(4):240-3. Available from: http://www.ijppr.com/index.php/IJPPR/article/view/1014
Section
Research Article